Anti-Inflammatory and Proresolving Lipid Mediators
نویسندگان
چکیده
منابع مشابه
Stereoselective synthesis of protectin D1: a potent anti-inflammatory and proresolving lipid mediator.
A convergent stereoselective synthesis of the potent anti-inflammatory, proresolving and neuroprotective lipid mediator protectin D1 (2) has been achieved in 15% yield over eight steps. The key features were a stereocontrolled Evans-aldol reaction with Nagao's chiral auxiliary and a highly selective Lindlar reduction of internal alkyne 23, allowing the sensitive conjugated E,E,Z-triene to be in...
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ژورنال
عنوان ژورنال: Annual Review of Pathology: Mechanisms of Disease
سال: 2008
ISSN: 1553-4006,1553-4014
DOI: 10.1146/annurev.pathmechdis.3.121806.151409